Acellular genomics

Our lab takes advantage of advances in single-cell genomics to study minute amounts of nuclei acids outside the context of naturally occurring cells. We aim to characterise the RNA content of biomolecular condensates, extracellular vesicles as well as cell-free RNA/DNA in order to address intriguing questions in medicine & synthetic biology.

We are part of the Department of RNA Bioinformatics and High-Throughput Sequencing Analysis at the University Jena and located at the Leibniz Institute on Aging (FLI).

news

Oct 16, 2023 Aaaand another one from Aram :fire:. His work on cell type contributions to the liver cancer cfRNA landscape is now out in Human Genomics. Huge congrats!
Sep 29, 2023 Two new papers out on bioRxiv about Detecting ligand-receptor signaling in blood and RNA-based fungal detection! Congrats to Aram & Julia!
Jan 10, 2023 Welcome to our new master student: Saeedeh Zamani!

latest publication

  1. Hum Genomics
    Decoding cell-type contributions to the cfRNA transcriptomic landscape of liver cancer
    Aram Safrastyan, Christian Höner Zu Siederdissen, and Damian Wollny
    Human Genomics 2023